Spleen findings in drowning

A retrospective study of spleen findings in 42 victims of drowning and a comparison group of 42 cases of asphyxiation due to other causes (hanging, ligature strangulation and manual strangulation), that were matched for sex, age, body weight and build, was performed. Significantly smaller spleen weights (P < 0.05), spleen weight:body weight ratios (P < 0.01) and spleen weight:liver weight ratios (P < 0.01) were found in the victims of drowning. The difference in weight was 18%. A significant negative correlation between spleen weight and blood alcohol concentration was found in the study group (r = −0.44; P < 0.01), but not in the control group. The possibility that the findings are due to a stress reaction caused by hypoxia in the presence of cooling and an influence of alcohol on reflex mechanisms is discussed

Phase Behavior of Short Range Square Well Model

Various Monte Carlo techniques are used to determine the complete phase diagrams of the square well model for the attractive ranges $\lambda = 1.15$ and $\lambda = 1.25$. The results for the latter case are in agreement with earlier Monte Carlo simulations for the fluid-fluid coexistence curve and yield new results for the liquidus-solidus lines. Our results for $\lambda = 1.15$ are new. We find that the fluid-fluid critical point is metastable for both cases, with the case $\lambda = 1.25$ being just below the threshold value for metastability. We compare our results with prior studies and with experimental results for the gamma-II crystallin.Comment: 8 figures, 1 tabl

A machine-learning derived model of seafloor sediment accumulation

Abstract Previous studies regarding the depositional pattern and quantity of accumulated seafloor sediment tend to be regional, limited in scope and involving costly and time-consuming geologic field campaigns and laboratory work. Presented herein is a global map of predicted modern (postindustrial, 20th and 21st century) oceanic mass accumulation rates of 5-arc-minute pitch and in log10-space, trained on observed marine mass accumulation rates from 43 peer reviewed sources (n = 1744) and predicted using a k-nearest neighbor geospatial algorithm. The resultant model predicts ~3.3 × 104 Mt. yr−1 of sediment accumulating onto the sea floor (R2 = 0.88). Most sediment accumulates proximal to major river outlets and deltas. Continental regions with the highest sediment accumulation are Asia and Oceania. This model is the first of its kind to predict the rate and quantity of sediment accumulating on to the ocean floor, globally, using decades of regional real-world observations. The generated global map of modern, benthic mass accumulation rates also serves to highlight areas of interest for future study in related fields, such as sediment dynamics and seafloor stability

New supersymmetric quartet of nuclei in the A=190 mass region

We present evidence for a new supersymmetric quartet in the A=190 region of the nuclear mass table. New experimental information on transfer and neutron capture reactions to the odd-odd nucleaus 194 Ir strongly suggests the existence of a new supersymmetric quartet, consisting of the 192,193 Os and 193,194 Ir nuclei. We make explicit predictions for the odd-neutron nucleus 193 Os, and suggest that its spectroscopic properties be measured in dedicated experiments.Comment: 5 pages, 4 figures, updated figures and revised text, Physical Review C, Rapid Communication, in pres

New supersymmetric quartet of nuclei in the A=190 mass region

We present evidence for a new supersymmetric quartet in the A=190 region of the nuclear mass table. New experimental information on transfer and neutron capture reactions to the odd-odd nucleaus 194 Ir strongly suggests the existence of a new supersymmetric quartet, consisting of the 192,193 Os and 193,194 Ir nuclei. We make explicit predictions for the odd-neutron nucleus 193 Os, and suggest that its spectroscopic properties be measured in dedicated experiments.Comment: 5 pages, 4 figures, updated figures and revised text, Physical Review C, Rapid Communication, in pres

Experimental and computational analyses reveal that environmental restrictions shape HIV-1 spread in 3D cultures

Here, using an integrative experimental and computational approach, Imle et al. show how cell motility and density affect HIV cell-associated transmission in a three-dimensional tissue-like culture system of CD4+ T cells and collagen, and how different collagen matrices restrict infection by cell-free virions

Circadian rhythms and sleep regulation in seasonal affective disorder

Seasonal affective disorder (SAD) is characterised by recurrent episodes in autumn and winter of depression, hypersomnia, augmented appetite with carbohydrate craving, and weight gain, and can be successfully treated with bright light. Circadian rhythm hypotheses (summarized in) have stimulated research into the pathophysiology of SAD, postulating that: 1.The illness is a consequence of delayed phase position, 2.It is correlated with diminished circadian amplitude, or 3.It results from changes in the nocturnal duration between dusk and dawn e.g. of low core body temperature or melatonin secretion. Light is considered to act directly on the circadian pacemaker (‘Process C') and not on sleep dependent processes (‘Process S'). Thus successful treatment of SAD must act via mechanisms within known retinohypothalamic pathways. Conversely, emergence of SAD symptoms may reflect inappropriate neurobiological response to decreasing daylengt

Spleen findings in drowning

A retrospective study of spleen findings in 42 victims of drowning and a comparison group of 42 cases of asphyxiation due to other causes (hanging, ligature strangulation and manual strangulation), that were matched for sex, age, body weight and build, was performed. Significantly smaller spleen weights (P < 0.05), spleen weight:body weight ratios (P < 0.01) and spleen weight:liver weight ratios (P < 0.01) were found in the victims of drowning. The difference in weight was 18%. A significant negative correlation between spleen weight and blood alcohol concentration was found in the study group (r = −0.44; P < 0.01), but not in the control group. The possibility that the findings are due to a stress reaction caused by hypoxia in the presence of cooling and an influence of alcohol on reflex mechanisms is discussed